import fitz
doc = fitz.open("some.pdf") # open pdf
page = doc[n] # open the page (0-based number)
rtab = [] # store all rectangles here
annot = page.firstAnnot # read first annotation
while annot:
rtab.append(annot.rect) # store rectangle
annot = annot.next # read next annot
i = len(rtab)-1 # point to last rectangle
annot = page.firstAnnot # cycle thru annots again
while annot:
annot.setRect(rtab[i]) # give it a new place
i -= 1 # count backwards
annot = annot.next
doc.save("some-reversed.pdf") # save PDF with reversed annotations
